Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA4 | P51532 | 7/20 | 0.64 |
| ▸ | PBRM1 | Q86U86 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21993751 | 0.82 | SMARCA4 (0.60) | SMARCA4PBRM1NPC1RAB9ACCR3 | |
| SCHEMBL21993209 | 0.78 | SMARCA4 (0.58) | SMARCA4PBRM1MAPTNPC1CYP1A2 | |
| SCHEMBL22794557 | 0.78 | SMARCA4 (1.00) | SMARCA4PBRM1MAPTNPC1CYP1A2 | |
| SCHEMBL21993276 | 0.78 | SMARCA4 (0.64) | SMARCA4PBRM1MAPTNPC1CYP1A2 | |
| SCHEMBL21992773 | 0.78 | SMARCA4 (0.57) | SMARCA4PBRM1MAPTNPC1CYP1A2 | |
| SCHEMBL22794560 | 0.77 | SMARCA4 (1.00) | SMARCA4PBRM1MAPTNPC1CYP1A2 | |
| SCHEMBL22794541 | 0.76 | SMARCA4 (1.00) | SMARCA4PBRM1MAPTNPC1CYP1A2 | |
| SCHEMBL21993284 | 0.75 | SMARCA4 (0.61) | SMARCA4PBRM1NPC1RAB9ACCR3 | |
| SCHEMBL21992956 | 0.75 | MEN1 (0.61) | SMARCA4PBRM1MAPTNPC1RAB9A | |
| SCHEMBL11085066 | 0.75 | RAB9A (0.54) | MAPTNPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11583530-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | GALECTIN SCIENCES, LLC (US) | 2023-02-21 | — | — | US | disclosed |
| US-20200147088-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | GALECTIN SCIENCES, LLC | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147088-A1 | Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof | LGALS1, LGALS2, LGALS3 | SMARCA4 4569/4885PBRM1 4399/4885MAPT 1108/4885 |
| US-11583530-B2 | Compounds for the prevention and treatment of medical disorders and uses thereof | LGALS1, LGALS2, LGALS3 | SMARCA4 4569/4885PBRM1 4399/4885MAPT 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.