Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21994192 | 0.83 | NPC1 (0.68) | ALDH1A1MAPTEPHX2RAB9AKDM4E | |
| SCHEMBL21994189 | 0.83 | NPC1 (0.72) | ALDH1A1MAPTEPHX2RAB9AKDM4E | |
| SCHEMBL21933276 | 0.83 | EPHX2 (0.65) | ALDH1A1MAPTEPHX2RAB9AKDM4E | |
| SCHEMBL21933245 | 0.76 | KDM4E (0.81) | ALDH1A1MAPTEPHX2RAB9AKDM4E | |
| SCHEMBL21994191 | 0.76 | EPHX2 (0.60) | ALDH1A1LMNAMAPTEPHX2HPGD | |
| SCHEMBL21933288 | 0.76 | SMN1; SMN2 (0.74) | ALDH1A1LMNATP53MAPTEPHX2 | |
| SCHEMBL872523 | 0.76 | ALDH1A1 (0.57) | ALDH1A1LMNATP53POLBHPGD | |
| SCHEMBL21998497 | 0.74 | EPHX2 (0.67) | ALDH1A1TP53MAPTEPHX2HPGD | |
| SCHEMBL19097940 | 0.74 | EPHX2 (0.70) | ALDH1A1LMNATP53MAPTEPHX2 | |
| SCHEMBL21933255 | 0.73 | EPHX2 (0.69) | ALDH1A1MAPTEPHX2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | STS, F12, GLB1 | ALDH1A1 449/4885LMNA 1887/4885TP53 2507/4885 |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | STS, F12, STK38L | ALDH1A1 415/4885LMNA 1896/4885TP53 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.