Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845510 | 0.88 | SCN3A (0.54) | — | |
| SCHEMBL10119592 | 0.85 | F2 (0.43) | ALDH1A1POLBHPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16741981 | 0.82 | SCN3A (0.52) | HPGD | |
| Hydrochloric Acid SCHEMBL16741983 | 0.82 | SCN3A (0.52) | HPGD | |
| SCHEMBL8236871 | 0.78 | SCN3A (0.48) | — | |
| SCHEMBL10119356 | 0.78 | CA12 (0.47) | POLBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL21994190 | 0.76 | ALDH1A1 (0.61) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL13388756 | 0.75 | SCN3A (0.64) | RAB9ALMNA | |
| SCHEMBL845457 | 0.74 | HPGD (0.55) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL7692273 | 0.74 | SCN3A (0.56) | ALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |