Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601108 | 0.86 | NPC1 (0.44) | PDE10AAKT1NPC1RAB9AKMT2A | |
| SCHEMBL29374375 | 0.82 | PSMB5 (0.65) | PDE10AAKT1PSMB5NPC1RAB9A | |
| SCHEMBL3359420 | 0.82 | PSMB5 (0.65) | PDE10AAKT1PSMB5NPC1RAB9A | |
| SCHEMBL1187275 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9AKMT2AMEN1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28129677 | 0.80 | PSMB5 (0.63) | PDE10AAKT1PSMB5NPC1RAB9A | |
| SCHEMBL31054483 | 0.80 | PSMB5 (0.63) | PDE10AAKT1PSMB5NPC1RAB9A | |
| SCHEMBL12854082 | 0.79 | PDE10A (0.55) | PDE10AAKT1PSMB5NPC1RAB9A | |
| SCHEMBL30302764 | 0.79 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL19369885 | 0.78 | AKT1 (0.45) | PDE10AAKT1PSMB5KMT2AMEN1 | |
| SCHEMBL29726817 | 0.76 | ACHE (0.56) | PDE10AKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102498084-B | Method for producing oxidation reaction product of aromatic compound | NATIONAL UNIVERSITY CORPORATION OSAKA UNIVERSITY (JP) | 2015-11-25 | — | — | CN | disclosed |
| EP-2479160-B1 | PROCESS FOR PRODUCTION OF OXIDATION REACTION PRODUCT OF AROMATIC COMPOUND | UNIV OSAKA (JP) | 2015-09-09 | — | — | EP | disclosed |
| EP-2479160-A1 | PROCESS FOR PRODUCTION OF OXIDATION REACTION PRODUCT OF AROMATIC COMPOUND | Osaka University (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120171111-A1 | PROCESS FOR PRODUCTION OF OXIDATION REACTION PRODUCT OF AROMATIC COMPOUND | OSAKA UNIVERSITY (JP) | 2012-07-05 | — | — | US | disclosed |
| CN-102498084-A | Method for producing oxidation reaction product of aromatic compound | UNIV OSAKA | 2012-06-13 | — | — | CN | disclosed |
| US-7977486-B2 | Quinolinium ion derivatives, process for the production of the derivatives, products made by using the same, and reduction and oxidation methods with the derivatives | OSAKA UNIVERSITY (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20100004454-A1 | QUINOLINIUM ION DERIVATIVES, PROCESS FOR THE PRODUCTION OF THE DERIVATIVES, PRODUCTS MADE BY USING THE SAME, AND REDUCTION AND OXIDATION METHODS WITH THE DERIVATIVES | OSAKA UNIVERSITY (JP) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171111-A1 | PROCESS FOR PRODUCTION OF OXIDATION REACTION PRODUCT OF AROMATIC COMPOUND | TYR, AOX1, POR | PDE10A 3527/4885AKT1 3575/4885PSMB5 1898/4885 |
| US-20100004454-A1 | QUINOLINIUM ION DERIVATIVES, PROCESS FOR THE PRODUCTION OF THE DERIVATIVES, PRODUCTS MADE BY USING THE SAME, AND REDUCTION AND OXIDATION METHODS WITH THE DERIVATIVES | APEX1, NQO1, POT1 | PDE10A 4673/4885AKT1 1806/4885PSMB5 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.