SCHEMBL2199470

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2201858	0.87	IKBKB (0.55)	IKBKBCHUKCSF1RBRD4CDC7
	SCHEMBL2199660	0.85	PARP1 (0.50)	IKBKBCHUKPARP1BRD4CDC7
	SCHEMBL2201619	0.84	BRD4 (0.45)	IKBKBPARP1BRD4CDC7RIPK1
	SCHEMBL2198026	0.82	CDC7 (0.57)	BRD4CDC7CCNA2CDK2CCNA1
	SCHEMBL2197274	0.82	CDC7 (0.57)	IKBKBBRD4CDC7CHEK1
	SCHEMBL12423887	0.82	BRD4 (0.59)	IKBKBCHUKPARP1BRD4CDC7
	SCHEMBL2198480	0.82	NPC1 (0.46)	IKBKBCHUKPARP1BRD4CDC7
	SCHEMBL12509725	0.82	BRD4 (0.44)	IKBKBBRD4CDC7RIPK1CCNA2
	SCHEMBL2198095	0.82	CDC7 (0.57)	CSF1RBRD4CDC7CHEK1
	SCHEMBL2200146	0.82	BRD4 (0.62)	IKBKBBRD4CDC7CCNA2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.