SCHEMBL21995155

SCHEMBL21995155

C=CC(=O)OCC=C(C)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.41
HPGD P15428 1/20 0.40
ALDH1A1 P00352 7/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
THRB P10828 2/20 0.34
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28099897 0.96 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23813370 0.82 ALDH1A1 (0.33) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28007306 0.82 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8425135 0.81 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28116127 0.80 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27465283 0.80 TSHR (0.52) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL29178049 0.79 ALDH1A1 (0.52) TSHRALDH1A1THRBCYP2D6CYP2C19
SCHEMBL28013262 0.79 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27975710 0.78 TSHR (0.64) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2024200 0.78 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3886882-A1 HAFNIA ALVEI FORMULATIONS Targedys (FR) 2021-10-06 EP disclosed
WO-2020109490-A1 HAFNIA ALVEI FORMULATIONS TARGEDYS (FR) 2020-06-04 WO disclosed
CN-105753858-B Heterocyclic compound and p27Kip1Decomposing inhibitor ASKA制药株式会社 2019-04-30 CN disclosed
CN-109254342-A Polarizing film 住友化学株式会社 2019-01-22 CN disclosed
CN-109153701-A The crystalline polymorphs of 15 beta-hydroxies-Osaterone acetate ASKA制药株式会社 2019-01-04 CN disclosed
CN-108349232-A The manufacturing method of laminated optical film 住友化学株式会社 2018-07-31 CN disclosed
CN-108139533-A The manufacturing method of stretched film and the manufacturing method of polarizing coating 住友化学株式会社 2018-06-08 CN disclosed
CN-107924008-A Polarization plates and image display device 住友化学株式会社 2018-04-17 CN disclosed
CN-107703578-A polarizer 住友化学株式会社 2018-02-16 CN disclosed
CN-104969100-B Laminate for polarizing plate, method for producing laminate for polarizing plate, and polarizing plate 日本合成化学工业株式会社 2018-01-23 CN disclosed
CN-101086539-B Adhesive for polarizing filter, polarizing filter and manufacturing method thereof, optical film and image display device NITTO DENKO CORP 2010-06-09 CN disclosed
CN-101692133-A Adhesive for polarizing plate, method for producing same, optical film, and image display device NITTO DENKO CORP 2010-04-07 CN disclosed
CN-101531873-A Pressure-sensitive adhesive composition for optical films, pressure-sensitive adhesive optical film and image display NITTO DENKO CORP (JP) 2009-09-16 CN disclosed
CN-101512399-A Polarizer protective film, polarizing plate, and image display device NITTO DENKO CORP (JP) 2009-08-19 CN disclosed
CN-101487912-A Polarizing plate, method for producing same, optical film, and image display device NITTO DENKO CORP (JP) 2009-07-22 CN disclosed
CN-101398501-A Polarizing plate, method for producing same, optical film, and image display device NITTO DENKO CORP (JP) 2009-04-01 CN disclosed
CN-101371172-A Method for producing polarizer, polarizer, polarizing plate, optical film and image display NITTO DENKO CORP (JP) 2009-02-18 CN disclosed
CN-101228462-A Polarizing plate and image display device NITTO DENKO CORP (JP) 2008-07-23 CN disclosed
CN-101104329-A Method for producing multilayer laminated film NITTO DENKO CORP (JP) 2008-01-16 CN disclosed
CN-101086539-A Adhesive for polarizing filter, polarizing filter and manufacturing method thereof, optical film and image display device NITTO DENKO CORP (JP) 2007-12-12 CN disclosed