Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007306 | 0.90 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL6368769 | 0.87 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28544460 | 0.83 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28013262 | 0.83 | TSHR (0.40) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28754452 | 0.83 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL5366050 | 0.82 | TSHR (0.50) | TSHRALDH1A1HPGDTHRBCYP2D6 | |
| SCHEMBL5025149 | 0.81 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL27530098 | 0.80 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL21995155 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8382801 | 0.79 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029046-B | Dental composition and application thereof | 3M创新有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-108366911-A | two-component self-adhesive dental composition, storage-stable initiator system and use thereof | 3M创新有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-104114142-B | One-component self-adhesive dental compositions, methods of making and using the same | 3M创新有限公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-106029046-A | Dental composition and use thereof | 3M创新有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106029044-A | Adhesive bonding composition and use thereof | 3M创新有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-104114142-A | One-component self-adhesive dental compositions, methods of making and using the same | 3M INNOVATIVE PROPERTIES CO | 2014-10-22 | — | — | CN | disclosed |
| CN-1170879-C | Fire-retardant resin composition and shaped article made of same | ������������ʽ���� | 2004-10-13 | — | — | CN | disclosed |
| CN-1275590-A | Fire-retardant resin composition and shaped article made of same | TORAY INDUSTRIES (JP) | 2000-12-06 | — | — | CN | disclosed |