SCHEMBL21995198

SCHEMBL21995198

CCC[CH]N(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
GLA P06280 1/20 0.38
TP53 P04637 2/20 0.37
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5071847 0.84 SOAT2 (0.43) TP53TDP1MEN1KMT2AKCNH2
SCHEMBL5146711 0.84 SOAT2 (0.43) TP53TDP1MEN1KMT2AKCNH2
SCHEMBL3684137 0.81 ALDH1A1 (0.40) ALDH1A1TSHRGLATP53MAPT
SCHEMBL6664264 0.78 TLR8 (0.36) ALDH1A1TSHRGLATP53MAPT
Butane SCHEMBL28208271 0.75 ALDH1A1 (0.55) ALDH1A1TSHRGLATP53MAPT
SCHEMBL5831023 0.70 MAOB (0.50) ALDH1A1TSHRTP53CYP2C19TRPA1
SCHEMBL8338521 0.70 TSHR (0.52) ALDH1A1TSHRTP53CYP3A4CYP2C19
SCHEMBL6662115 0.68 ALDH1A1 (0.38) ALDH1A1TSHRGLATP53MAPT
SCHEMBL2960795 0.67 MEN1 (0.40) ALDH1A1TSHRGLAMAPTHTT
SCHEMBL9193487 0.67 TSHR (0.37) ALDH1A1TSHRGLATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3887428-A1 RESIN BLENDS INCLUDING PHTHALONITRILE RESIN AND THIADIAZOLE SUBSTITUTED PHTHALONITRILE COMPOUND, ARTICLES, COMPOUNDS, AND METHODS 3M Innovative Properties Company (US) 2021-10-06 EP disclosed
WO-2020109902-A1 RESIN BLENDS INCLUDING PHTHALONITRILE RESIN AND THIADIAZOLE SUBSTITUTED PHTHALONITRILE COMPOUND, ARTICLES, COMPOUNDS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-06-04 WO disclosed