Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.33 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21995428 | 0.89 | PRKAB2 (0.34) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL21995407 | 0.85 | RORC (0.32) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL12556961 | 0.78 | PDE2A (0.42) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL13002319 | 0.78 | NOTUM (0.35) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL18075609 | 0.75 | PDE2A (0.40) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL21180457 | 0.75 | PDE2A (0.40) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL5584686 | 0.75 | HTR2C (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5584684 | 0.75 | NOTUM (0.40) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL21995301 | 0.74 | TSHR (0.60) | PDK2CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL9911475 | 0.74 | IDO1 (0.46) | KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |