Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 3/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21995465 | 0.89 | PDE2A (0.38) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL21995407 | 0.84 | RORC (0.32) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5216028 | 0.72 | QDPR (0.43) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL5584686 | 0.69 | HTR2C (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5584684 | 0.69 | NOTUM (0.40) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL13002319 | 0.69 | NOTUM (0.35) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL21995301 | 0.68 | TSHR (0.60) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL12556961 | 0.68 | PDE2A (0.42) | PDE2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL25247362 | 0.67 | HTR3A (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL23605496 | 0.67 | QDPR (0.50) | SLC6A2SLC6A4SLC6A3HTR1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |