Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10467442 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2KIF11KITBRAFRECQL | |
| SCHEMBL2497478 | 0.77 | KIF11 (0.51) | SMN1; SMN2KIF11KITBRAFRECQL | |
| SCHEMBL15553344 | 0.77 | BRAF (0.58) | SMN1; SMN2KIF11KITBRAFRECQL | |
| Hydrochloric Acid SCHEMBL1882259 | 0.75 | KIF11 (0.50) | SMN1; SMN2KIF11KITBRAFRECQL | |
| SCHEMBL22058802 | 0.75 | ALDH1A1 (0.66) | SMN1; SMN2CYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL10467440 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2KITBRAFRECQLADORA3 | |
| SCHEMBL8518362 | 0.74 | CYP1A2 (0.48) | SMN1; SMN2KIF11BRAFRECQLADORA3 | |
| SCHEMBL22879139 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AADORA3ADORA2AADORA2B | |
| SCHEMBL19678085 | 0.73 | KIT (0.56) | SMN1; SMN2KITBRAFKMT2AALDH1A1 | |
| SCHEMBL22879093 | 0.73 | MAPT (0.59) | SMN1; SMN2KMT2ACYP1A2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002296-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-01-06 | — | — | US | disclosed |
| EP-3886848-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | Rutgers, The State University of New Jersey (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020112845-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020112845-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002296-A1 | PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS | BMI1, GLI1, MCL1 | SMN1; SMN2 543/4885KIF11 2438/4885KIT 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.