SCHEMBL2199592

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13630537	0.89	BRD4 (0.45)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2197555	0.87	BRD4 (0.49)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2200493	0.86	BRD4 (0.46)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2196927	0.86	CDC7 (0.54)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2198470	0.85	BRD4 (0.47)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL12509787	0.84	KMT2A (0.50)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2199883	0.84	CHEK1 (0.45)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2199427	0.83	MAPT (0.55)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2195870	0.83	KDM4E (0.50)	BRD4CHUKINSRMAPK8CAMKK2
	SCHEMBL2197053	0.83	BRD4 (0.47)	BRD4HTTMCL1IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.