Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL792729 | 0.96 | ALDH1A1 (0.46) | NPC1TSHRALDH1A1CYP3A4ABCC4 | |
| SCHEMBL28933725 | 0.95 | ALDH1A1 (0.48) | NPC1TSHRALDH1A1CYP3A4ABCC4 | |
| SCHEMBL1130528 | 0.93 | TSHR (0.43) | NPC1TSHRALDH1A1CYP3A4MAPT | |
| SCHEMBL2193178 | 0.91 | NPC1 (0.40) | NPC1TSHRALDH1A1CYP3A4ABCC4 | |
| Succinic Acid SCHEMBL31375868 | 0.91 | NPC1 (0.40) | NPC1TSHRALDH1A1CYP3A4ABCC4 | |
| SCHEMBL15845250 | 0.91 | TSHR (0.47) | NPC1TSHRALDH1A1CYP3A4GAA | |
| SCHEMBL15844644 | 0.91 | TSHR (0.47) | NPC1TSHRALDH1A1CYP3A4GAA | |
| SCHEMBL15844732 | 0.89 | DGKA (0.41) | NPC1TSHRALDH1A1CYP3A4MAPT | |
| SCHEMBL218168 | 0.89 | DGKA (0.45) | TSHRALDH1A1CYP3A4GAADGKA | |
| SCHEMBL15844859 | 0.87 | DGKA (0.48) | TSHRALDH1A1CYP3A4DGKAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171431-A1 | FINE STRUCTURE AND STAMPER FOR IMPRINTING | HITACHI, LTD. (JP) | 2011-07-14 | — | — | US | disclosed |