Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29840027 | 0.99 | GLP1R (0.36) | GLP1RGAATDP1KDM4EUSP2 | |
| SCHEMBL12480931 | 0.82 | KDM4E (0.40) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL21996632 | 0.75 | GAA (0.40) | GAATDP1 | |
| SCHEMBL21996592 | 0.68 | HTR6 (0.41) | GAATDP1KDM4EALDH1A1LMNA | |
| SCHEMBL2797476 | 0.65 | ALDH1A1 (0.39) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL28647325 | 0.65 | GAA (0.33) | GLP1RGAATDP1 | |
| SCHEMBL12482112 | 0.64 | — | — | |
| SCHEMBL15333917 | 0.64 | — | — | |
| SCHEMBL12481402 | 0.64 | — | — | |
| SCHEMBL4946961 | 0.64 | KDM4E (0.47) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887364-A1 | AROMATIC COMPOUNDS FOR USE IN ACTIVATING HEMATOPOIETIC STEM AND PROGENITOR CELLS | Celularity Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020113178-A1 | AROMATIC COMPOUNDS FOR USE IN ACTIVATING HEMATOPOIETIC STEM AND PROGENITOR CELLS | Celularity, Inc. (US) | 2020-06-04 | — | — | WO | disclosed |