SCHEMBL21999231

SCHEMBL21999231

COCC1OC(n2cc(C)c(N)nc2=O)C(OC)C1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADK P55263 3/20 0.42
ADORA3 P0DMS8 1/20 0.42
ALDH1A1 P00352 2/20 0.39
HTT P42858 2/20 0.39
P2RY6 Q15077 1/20 0.37
RNASEL Q05823 2/20 0.37
LMNA P02545 2/20 0.37
MTOR P42345 2/20 0.37
THRB P10828 1/20 0.37
MDM2 Q00987 1/20 0.37
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
GMNN O75496 1/20 0.37
TP53 P04637 1/20 0.37
NFKB1 P19838 1/20 0.37
DNMT1 P26358 1/20 0.37
THPO P40225 1/20 0.37
RAB9A P51151 1/20 0.37
BLM P54132 1/20 0.37
HBB P68871 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21999788 0.90 ADK (0.40) ADKADORA3ALDH1A1HTTP2RY6
SCHEMBL16805336 0.90 LMNA (0.47) ALDH1A1HTTLMNAMTORTHRB
SCHEMBL15810727 0.90 LMNA (0.47) ALDH1A1HTTLMNAMTORTHRB
SCHEMBL18512865 0.90 LMNA (0.47) ALDH1A1HTTLMNAMTORTHRB
SCHEMBL659091 0.90 LMNA (0.47) ALDH1A1HTTLMNAMTORTHRB
SCHEMBL23547665 0.90 LMNA (0.37) ADORA3ALDH1A1HTTP2RY6RNASEL
SCHEMBL22261563 0.90 LMNA (0.47) ALDH1A1HTTLMNAMTORTHRB
SCHEMBL659090 0.90 LMNA (0.47) ALDH1A1HTTLMNAMTORTHRB
SCHEMBL22855719 0.90 ADK (0.35) ADKADORA3ALDH1A1HTTP2RY6
SCHEMBL12590080 0.90 ADK (0.35) ADKADORA3ALDH1A1HTTP2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200147124-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS ALIGOS THERAPEUTICS, INC. 2020-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200147124-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS RNGTT, PHAX, HAVCR2 ADK 1820/4885ADORA3 1372/4885ALDH1A1 3336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.