Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001368 | 0.90 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL22001749 | 0.82 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL22001276 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21043084 | 0.82 | NPC1 (0.47) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21043049 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21043060 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21042783 | 0.79 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21043130 | 0.78 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21043462 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL22001176 | 0.74 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-B1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2020-05-13 | — | — | EP | disclosed |