Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119647 | 0.83 | ALOX5 (0.47) | ALOX5MAPK1LMNATDP1ALDH1A1 | |
| SCHEMBL10588542 | 0.83 | ALOX5 (0.47) | ALOX5MAPK1LMNATDP1ALDH1A1 | |
| SCHEMBL10629661 | 0.82 | ALOX5 (0.46) | ALOX5MAPK1LMNATDP1ALDH1A1 | |
| SCHEMBL12988355 | 0.81 | MAPT (0.58) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL14072751 | 0.81 | NPC1 (0.56) | ALOX5MAPK1LMNATDP1ALDH1A1 | |
| SCHEMBL29864803 | 0.81 | NPC1 (0.56) | ALOX5MAPK1LMNATDP1ALDH1A1 | |
| SCHEMBL30142113 | 0.77 | ALOX5 (0.65) | ALOX5MAPK1LMNATDP1ALDH1A1 | |
| SCHEMBL2045141 | 0.77 | ALOX5 (0.65) | ALOX5MAPK1LMNATDP1ALDH1A1 | |
| SCHEMBL15177571 | 0.76 | ALDH1A1 (0.47) | LMNATDP1ALDH1A1KDM4EMAPT | |
| SCHEMBL3147510 | 0.75 | ALOX5 (0.51) | ALOX5MAPK1LMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493454-B | Quinolizine aza double aromatic ring axial chiral compound and its synthesis method | 南京理工大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-113493454-A | Quinolizine aza double aromatic ring axial chiral compound and its synthesis method | 南京理工大学 | 2021-10-12 | — | — | CN | disclosed |
| EP-1964861-B1 | ACETYLENE-BASED POLYMER | NAT INST OF ADVANCED IND SCIEN (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-7977441-B2 | Acetylene-based polymer | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20090253872-A1 | Acetylene-Based Polymer | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-1964861-A1 | ACETYLENE POLYMER | National Institute of Advanced Industrial Science and Technology (JP) | 2008-09-03 | — | — | EP | disclosed |