Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14072751 | 1.00 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL2200144 | 0.81 | ALOX5 (0.47) | RAB9AMAPTL3MBTL1LMNAHPGD | |
| SCHEMBL8859833 | 0.77 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19608995 | 0.76 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL4078645 | 0.76 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL30822036 | 0.76 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL2386082 | 0.76 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL5654886 | 0.76 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL29860529 | 0.76 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL27512292 | 0.76 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057885-B | Styrene axis chiral phosphine ligand and synthetic method and application thereof | 上海交通大学 | 2023-10-17 | — | — | CN | disclosed |
| CN-115057885-A | Styrene axis chiral phosphine ligand and synthetic method and application thereof | 上海交通大学 | 2022-09-16 | — | — | CN | disclosed |