SCHEMBL22004565

SCHEMBL22004565

CCSNCc1cncc(Br)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21535337 0.82 PKM (0.30)
SCHEMBL31260022 0.73 CYP11B2 (0.36)
SCHEMBL14780080 0.73 CYP11B2 (0.36)
SCHEMBL21535294 0.72
SCHEMBL16196135 0.69
SCHEMBL17748267 0.69 CD274 (0.38)
SCHEMBL20565600 0.69 CD274 (0.41)
SCHEMBL21800568 0.69 CD274 (0.41)
SCHEMBL29385422 0.69 CD274 (0.41)
SCHEMBL21535264 0.68 PKM (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653618-A1 NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2020-05-20 EP disclosed