Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22004565 | 0.82 | SLC6A2 (0.32) | — | |
| SCHEMBL112117 | 0.77 | MAP3K8 (0.36) | — | |
| SCHEMBL6508284 | 0.77 | SLC6A2 (0.39) | — | |
| SCHEMBL6507540 | 0.72 | LMNA (0.34) | — | |
| SCHEMBL14779603 | 0.72 | CYP11B2 (0.38) | — | |
| SCHEMBL31260009 | 0.72 | CYP11B2 (0.38) | — | |
| SCHEMBL21535264 | 0.69 | PKM (0.40) | PKM | |
| SCHEMBL14780348 | 0.69 | AOC3 (0.35) | — | |
| SCHEMBL5794503 | 0.69 | PDXK (0.37) | — | |
| SCHEMBL6503187 | 0.67 | AOC3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653618-A1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2020-05-20 | — | — | EP | disclosed |
| EP-2755963-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-10-30 | — | — | EP | disclosed |