SCHEMBL2200481

SCHEMBL2200481

CCCCCCCCC=CCCCCCCCC(=O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 5/20 0.57
CETP P11597 1/20 0.53
DGKA P23743 1/20 0.47
SELP P16109 1/20 0.47
APP P05067 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15540605 1.00 TLR4 (0.57) TLR4CETPDGKASELPAPP
SCHEMBL2200474 1.00 TLR4 (0.57) TLR4CETPDGKASELPAPP
SCHEMBL2200475 1.00 TLR4 (0.57) TLR4CETPDGKASELPAPP
SCHEMBL28470234 1.00 TLR4 (0.57) TLR4CETPDGKASELPAPP
SCHEMBL2598250 1.00 TLR4 (0.57) TLR4CETPDGKASELPAPP
SCHEMBL65627 1.00 TLR4 (0.57) TLR4CETPDGKASELPAPP
Formaldehyde SCHEMBL17748792 0.98 TLR4 (0.55) TLR4CETPDGKASELPAPP
SCHEMBL2196892 0.96 TLR4 (0.59) TLR4CETP
SCHEMBL2196896 0.96 TLR4 (0.59) TLR4CETP
SCHEMBL5436079 0.96 TLR4 (0.59) TLR4CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 EP claimed
EP-2861205-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2015-04-22 EP claimed
WO-2013186485-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2013-12-19 WO claimed
EP-1837341-B1 Derivative of glucose and vitamin F, compositions containing it, its uses to improve the state of hair OREAL (FR) 2011-08-03 EP claimed
US-7763587-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-07-27 US claimed
EP-1837341-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'Oréal (FR) 2007-09-26 EP claimed
EP-1371658-B1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation OREAL (FR) 2007-09-12 EP claimed
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin L'OREAL (FR) 2006-07-27 US claimed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 EP claimed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 WO claimed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 US claimed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 EP claimed
EP-2861205-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2015-04-22 EP disclosed
US-8729254-B2 Derivative of glucose and vitamin F, compositions comprising it, uses and preparation process L'OREAL (FR) 2014-05-20 US disclosed
WO-2013186485-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2013-12-19 WO disclosed
EP-1837341-B1 Derivative of glucose and vitamin F, compositions containing it, its uses to improve the state of hair OREAL (FR) 2011-08-03 EP disclosed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 EP disclosed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 WO disclosed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 US disclosed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885CETP 1496/4885DGKA 584/4885
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin CUTA, SCD5, SCD TLR4 685/4885CETP 654/4885DGKA 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.