Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705419 | 0.92 | KDM4E (0.44) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL22005040 | 0.92 | KDM4E (0.44) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL22005008 | 0.90 | NPC1 (0.47) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL30519457 | 0.89 | MAPT (0.42) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL1144804 | 0.89 | MAPT (0.42) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL23630245 | 0.86 | KDM4E (0.40) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL21475436 | 0.86 | KDM4E (0.40) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL10458218 | 0.86 | KDM4E (0.45) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL91232 | 0.86 | ALDH1A1 (0.50) | MAPTLMNAJAK2GAAALDH1A1 | |
| SCHEMBL9968957 | 0.86 | CYP1A2 (0.47) | MAPTLMNAJAK2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168161-B2 | Biaryl phenoxy group IV transition metal catalysts for olefin polymerization | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200157254-A1 | BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYERMIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168161-B2 | Biaryl phenoxy group IV transition metal catalysts for olefin polymerization | PPOX, LIG4, PARG | MAPT 769/4885LMNA 3161/4885JAK2 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.