Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560592 | 0.89 | LMNA (0.42) | ALDH1A1RECQLIDO1LMNAGAA | |
| SCHEMBL16560595 | 0.88 | ALDH1A1 (0.42) | ALDH1A1RECQLIDO1LMNAGAA | |
| SCHEMBL22005000 | 0.86 | MAPT (0.50) | ALDH1A1RECQLIDO1LMNAGAA | |
| SCHEMBL22005040 | 0.84 | KDM4E (0.44) | ALDH1A1LMNAGAAJAK2MAPT | |
| SCHEMBL2705419 | 0.84 | KDM4E (0.44) | ALDH1A1RECQLLMNAGAAJAK2 | |
| SCHEMBL29510942 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RECQLIDO1LMNAGAA | |
| SCHEMBL238824 | 0.84 | ALDH1A1 (0.61) | ALDH1A1RECQLIDO1LMNAGAA | |
| SCHEMBL10458218 | 0.83 | KDM4E (0.45) | ALDH1A1LMNAGAAJAK2MAPT | |
| SCHEMBL22005008 | 0.82 | NPC1 (0.47) | ALDH1A1LMNAGAAJAK2MAPT | |
| SCHEMBL18525261 | 0.82 | ALDH1A1 (0.41) | ALDH1A1RECQLIDO1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219866-A1 | THERMOPLASTIC POLYURETHANE AND USES THEREOF | HUNTSMAN INTERNATIONAL LLC (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023183298-A1 | THERMOPLASTIC POLYURETHANE BINDER AND USES THEREOF | HUNTSMAN INTERNATIONAL LLC (US) | 2023-09-28 | — | — | WO | disclosed |
| US-10258602-B2 | Macrocyclic ghrelin receptor modulators and methods of using the same | OCERA THERAPEUTICS, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20180110824-A1 | Macrocyclic Modulators of the Ghrelin Receptor | OCERA THERAPEUTICS, INC. | 2018-04-26 | — | — | US | disclosed |
| US-20180110824-A1 | Macrocyclic Modulators of the Ghrelin Receptor | OCERA THERAPEUTICS, INC. | 2018-04-26 | — | — | US | disclosed |
| US-9949949-B2 | Macrocyclic ghrelin receptor modulators and methods of using the same | OCERA THERAPEUTICS, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9949949-B2 | Macrocyclic ghrelin receptor modulators and methods of using the same | OCERA THERAPEUTICS, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| EP-2457893-B1 | Intermediates for macrocyclic modulators of the ghrelin receptor | OCERA THERAPEUTICS INC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20170042858-A1 | MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME | MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY | 2017-02-16 | — | — | US | disclosed |
| US-20170042858-A1 | MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME | MALLINCKRODT PHARMA IP TRADING UNLIMITED COMPANY | 2017-02-16 | — | — | US | disclosed |
| EP-0794774-B1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2005-10-12 | — | — | EP | disclosed |
| US-5977122-A | 4,4-(disubstituted)cyclohexan-1-ols monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5891883-A | 4,4-(disubstituted)cyclohexan-1-ols monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-06 | — | — | US | disclosed |
| US-5892098-A | 3,3-(disubstituted)cyclohexan-1-one monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0828493-A4 | 4.4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS-MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0794774-A4 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0828493-A1 | 4.4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS-MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-18 | — | — | EP | disclosed |
| EP-0794774-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996038150-A1 | 4.4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS-MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996019988-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-OLS MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110824-A1 | Macrocyclic Modulators of the Ghrelin Receptor | GHSR, GIPR, GHRHR | ALDH1A1 3993/4885RECQL 3249/4885IDO1 3988/4885 |
| US-10258602-B2 | Macrocyclic ghrelin receptor modulators and methods of using the same | GHSR, GHRHR, GIPR | ALDH1A1 4297/4885RECQL 3140/4885IDO1 4167/4885 |
| US-20170042858-A1 | MACROCYCLIC GHRELIN RECEPTOR MODULATORS AND METHODS OF USING THE SAME | GHSR, GHRHR, GIPR | ALDH1A1 4245/4885RECQL 3242/4885IDO1 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.