Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13165476 | 0.78 | DPP4 (0.39) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL15099990 | 0.78 | DPP4 (0.39) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL24734661 | 0.76 | ATM (0.39) | DPP4DPP8DPP9 | |
| SCHEMBL20798666 | 0.74 | RIPK1 (0.40) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL3664998 | 0.72 | DPP4 (0.41) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL19201280 | 0.71 | — | — | |
| SCHEMBL20221847 | 0.69 | DPP4 (0.38) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL17225490 | 0.69 | DPP4 (0.46) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL7889534 | 0.68 | SMN1; SMN2 (0.39) | RIPK1DPP4DPP8DPP9 | |
| SCHEMBL20811182 | 0.66 | NR1H2 (0.41) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3095797-B1 | ANTI DLL3 ANTIBODIES AND METHODS OF USE THEREOF | ABBVIE STEMCENTRX LLC (US) | 2020-05-20 | — | — | EP | disclosed |