SCHEMBL2200585

SCHEMBL2200585

NSc1ccc2ccccc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 3/20 0.52
NOS2 P35228 1/20 0.52
BACE1 P56817 1/20 0.52
RXFP1 Q9HBX9 5/20 0.50
PRNP P04156 5/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 6/20 0.47
NPSR1 Q6W5P4 4/20 0.47
MAPK10 P53779 2/20 0.47
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
CYP1A2 P05177 1/20 0.46
RAB9A P51151 3/20 0.46
HPGD P15428 3/20 0.45
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
NPC1 O15118 2/20 0.42
MAPT P10636 4/20 0.42
GLA P06280 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899659 0.81 RXFP1 (0.53) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL2098479 0.81 RXFP1 (0.53) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL5807877 0.77 RXFP1 (0.51) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL2817162 0.77 CYP1A2 (0.58) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL10410970 0.77 RXFP1 (0.50) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL29979791 0.77 CYP1A2 (0.58) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL4370424 0.77 RXFP1 (0.50) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL11326601 0.77 RXFP1 (0.50) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL10411067 0.77 RXFP1 (0.50) NCF1NOS2BACE1RXFP1PRNP
SCHEMBL11029724 0.77 PRNP (0.59) NCF1NOS2BACE1RXFP1PRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090179553-A1 ELECTROLUMINESCENT MATERIAL CONTAINING AN ORGANIC LUMINESCENT SUBSTANCE INSTITUT PROBLEM KHIMICESKON FIZKI ROSSIISKOI AKADEMII NAUK (IPKHF RAN) (RU) 2009-07-16 US disclosed
CN-101437920-A Electroluminescent material containing organic luminescent material INST KHIM FIZ ROSSIISKOI AK (RU) 2009-05-20 CN disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-2039736-A1 ELECTROLUMINESCENT MATERIAL CONTAINING AN ORGANIC LUMINESCENT SUBSTANCE Institut Problem Khimicheskoi Fiziki Rossiiskoi AK (RU) 2009-03-25 EP disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed
WO-2008024018-A1 ELECTROLUMINESCENT MATERIAL CONTAINING AN ORGANIC LUMINESCENT SUBSTANCE INSTITUT PROBLEM KHIMICHESKOI FIZIKI ROSSIISKOI AKADEMII NAUK (IPKHF RAN) (RU) 2008-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 NCF1 1988/4885NOS2 1785/4885BACE1 4065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.