SCHEMBL4370424

SCHEMBL4370424

SSc1ccc2ccccc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 5/20 0.50
▸ PRNP P04156 5/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ NPSR1 Q6W5P4 4/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ MAPK10 P53779 2/20 0.47
▸ NCF1 P14598 3/20 0.46
▸ CYP1A2 P05177 2/20 0.46
▸ NOS2 P35228 1/20 0.46
▸ BACE1 P56817 1/20 0.46
▸ CA12 O43570 1/20 0.46
▸ CA9 Q16790 1/20 0.46
▸ RAB9A P51151 3/20 0.46
▸ HPGD P15428 2/20 0.45
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ GLA P06280 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ ACHE P22303 1/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2098479 0.81 RXFP1 (0.53) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL6899659 0.81 RXFP1 (0.53) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL10410970 0.77 RXFP1 (0.50) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL10411067 0.77 RXFP1 (0.50) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL5807877 0.77 RXFP1 (0.51) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL29979791 0.77 CYP1A2 (0.58) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL2200585 0.77 NCF1 (0.52) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL2817162 0.77 CYP1A2 (0.58) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL11326601 0.77 RXFP1 (0.50) RXFP1PRNPKDM4ENPSR1ALDH1A1
SCHEMBL7857102 0.76 PRNP (0.49) RXFP1PRNPKDM4ENPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4314324-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS Ultima Genomics, Inc. (US) 2024-02-07 — — EP claimed
WO-2022212408-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. (US) 2022-10-06 — — WO claimed
US-6989263-B1 Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2006-01-24 — — US claimed
US-20030198648-A1 Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA ACHILION PHARMACEUTICALS 2003-10-23 — — US claimed
WO-2003060098-A2 METHODS FOR IDENTIFYING COMPOUNDS WHICH INHIBIT BINDING OF NUCLEOCAPSID 7 PROTEIN TO HIV-1 RNA ACHILLION PHARMACEUTICALS, INC. (US) 2003-07-24 — — WO claimed
EP-0782632-B1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN US GOV HEALTH & HUMAN SERV (US) 2003-04-16 — — EP claimed
US-6001555-A DISSOCIATING A ZINC FINGER BY CONTACTING THE PROTEIN WITH A DISULFIDE, A MALEIMIDE, AN ALPHA-HALOGENATED KETONE, A HYDRAZIDE, A NITRIC OXIDE OR DERIVATIVES, CUPRIC IONS, FERRIC IONS OR THEIR COMPLEXES; SYNERGISTIC EFFECTS WITH VIRICIDES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-14 — — US claimed
EP-0782632-A1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services (US) 1997-07-09 — — EP claimed
WO-1996009406-A9 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN — 1996-05-23 — — WO claimed
WO-1996009406-A1 A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-03-28 — — WO claimed
US-20240132955-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. 2024-04-25 — — US disclosed
EP-4314324-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS Ultima Genomics, Inc. (US) 2024-02-07 — — EP disclosed
WO-2022212408-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. (US) 2022-10-06 — — WO disclosed
CN-104448700-B Resin combination 味之素株式会社 2019-01-22 — — CN disclosed
US-20160160178-A1 IMMUNOTHERAPY USING STEM CELLS WHITE OAK IND INC (US) 2016-06-09 — — US disclosed
EP-0417057-B1 Heterocyclic thiol-based sulfenimide compounds and rubber compositions containing them MONSANTO CO (US) 1995-03-01 — — EP disclosed
US-5260454-A Cure accelerator for natural and synthetic rubber; imroved cure rate, longer scorch delay MONSANTO COMPANY (US) 1993-11-09 — — US disclosed
US-5189174-A Rubber curing agent MONSANTO COMPANY (US) 1993-02-23 — — US disclosed
US-5079305-A Improved cure rate, scorch delay and reversion resistance MONSANTO COMPANY (US) 1992-01-07 — — US disclosed
EP-0417057-A2 Heterocyclic thiol-based sulfenimide compounds and rubber compositions containing them MONSANTO COMPANY (US) 1991-03-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160160178-A1 IMMUNOTHERAPY USING STEM CELLS CD14, ICOS, BMP4 RXFP1 2083/4885PRNP 3393/4885KDM4E 562/4885
US-20030198648-A1 Methods for identifying compounds which inhibit binding of nucleocapsid 7 protein to HIV-1 RNA MRPS27, SNRPE, NSUN2 RXFP1 4374/4885PRNP 626/4885KDM4E 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback