Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2202815 | 0.99 | TSHR (0.44) | TSHRHRH3MAPTKMT2ABCHE | |
| SCHEMBL15161920 | 0.81 | DRD2 (0.44) | HRH3MAPTBCHE | |
| SCHEMBL2203077 | 0.80 | HRH3 (0.46) | HRH3MAPTBCHE | |
| SCHEMBL12509872 | 0.80 | LMNA (0.41) | MAPTKMT2A | |
| SCHEMBL1638251 | 0.80 | DRD2 (0.40) | HRH3MAPTKMT2ABCHE | |
| SCHEMBL1638259 | 0.80 | HRH3 (0.43) | HRH3MAPT | |
| SCHEMBL2203383 | 0.79 | MAPT (0.57) | HRH3MAPT | |
| SCHEMBL1638613 | 0.78 | LOXL2 (0.41) | HRH3MAPT | |
| SCHEMBL2203825 | 0.78 | TSHR (0.44) | TSHRBCHE | |
| SCHEMBL1638551 | 0.77 | HRH3 (0.52) | HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |