SCHEMBL220073

SCHEMBL220073

Nc1ccc(Cl)cc1C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
KMT2A Q03164 3/20 0.63
KDM4E B2RXH2 3/20 0.63
GFER P55789 2/20 0.63
TP53 P04637 1/20 0.63
RXFP1 Q9HBX9 1/20 0.63
RECQL P46063 2/20 0.61
POLB P06746 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
MEN1 O00255 1/20 0.61
USP2 O75604 1/20 0.61
MAPT P10636 1/20 0.61
THRB P10828 1/20 0.61
PKM P14618 1/20 0.61
APEX1 P27695 1/20 0.61
BLM P54132 1/20 0.61
MCL1 Q07820 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CYP3A4 P08684 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31542015 1.00 ALDH1A1 (0.63) ALDH1A1KMT2AKDM4EGFERTP53
Hydrochloric Acid SCHEMBL4355655 0.98 KMT2A (0.64) ALDH1A1KMT2AKDM4EGFERTP53
Ammonia Solution, Strong SCHEMBL2320305 0.98 ALDH1A1 (0.61) ALDH1A1KMT2AKDM4EGFERTP53
Nitrogen SCHEMBL28649205 0.96 ALDH1A1 (0.59) ALDH1A1KMT2AKDM4EGFERTP53
Aminobenzoic Acid SCHEMBL10434210 0.88 KMT2A (0.58) ALDH1A1KMT2AKDM4EGFERTP53
SCHEMBL28356361 0.85 RECQL (0.73) ALDH1A1KMT2AKDM4EGFERTP53
SCHEMBL9540049 0.84 RECQL (0.79) ALDH1A1KMT2AKDM4EGFERTP53
SCHEMBL5707631 0.83 RECQL (0.56) ALDH1A1KMT2AKDM4EGFERTP53
SCHEMBL128885 0.83 SMN1; SMN2 (0.63) ALDH1A1KMT2AKDM4EGFERTP53
SCHEMBL620233 0.83 RECQL (0.59) ALDH1A1KMT2AKDM4EGFERTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1956 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924202-A Chrome-free tanning agent containing carboxylic acid sulfonate structure and preparation method thereof 浙江康诺和新材料有限公司 2024-04-26 CN claimed
CN-117720426-A Synthesis method of 2-amino-5-chloro-3-methylbenzoic acid 湖北泰盛化工有限公司 2024-03-19 CN claimed
CN-115181031-B Preparation method of 2-amino-5-chlorobenzoic acid derivative 江苏扬农化工股份有限公司 2024-03-15 CN claimed
CN-115010671-B One-step synthesis method of 2-substituted quinazolinone 江苏大学 2023-10-10 CN claimed
CN-115181031-A Preparation method of 2-amino-5-chlorobenzoic acid derivative 江苏扬农化工股份有限公司 2022-10-14 CN claimed
CN-113233990-B Preparation method of 5-chloro-2-aminobenzoic acid intermediate 江苏超跃化学有限公司 2022-09-23 CN claimed
CN-115010671-A One-step synthesis method of 2-substituted quinazolinone 江苏大学 2022-09-06 CN claimed
CN-113551954-A Enzymolysis method for enzymolysis of tissue sample by mild reducing agent and mass spectrum detection method thereof 复旦大学 2021-10-26 CN claimed
CN-113233990-A Preparation method of 5-chloro-2-aminobenzoic acid intermediate 江苏超跃化学有限公司 2021-08-10 CN claimed
CN-112105734-A Method for producing tryptamine 新图集生物技术有限责任公司 2020-12-18 CN claimed
EP-1386660-B1 Isolation of immunoglobulins UPFRONT CHROMATOGRAPHY AS (DK) 2009-09-02 EP claimed
US-7442779-B2 Isolation of proteins UPFRONT CHROMATOGRAPHY A/S (DK) 2008-10-28 US claimed
CN-1284773-C Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application BAIRUI GLOBAL CO LTD (VG) 2006-11-15 CN claimed
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
CN-1477099-A O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same 百瑞全球有限公司 2004-02-25 CN claimed
EP-0864587-B1 Aqueous binder based on polybutadiene DEGUSSA (DE) 2003-08-20 EP claimed
US-5744638-A Process for the preparation of haloanthranilic acids RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1998-04-28 US claimed
EP-0518374-B1 A process for the preparation of alkyl 3-chloroanthranilates DOWELANCO (US) 1996-05-01 EP claimed
EP-0518374-A2 A process for the preparation of alkyl 3-chloroanthranilates DOWELANCO (US) 1992-12-16 EP claimed
US-5118832-A 1,2-dichloro-5,5-dimethylhydantoin chlorinating agent; selective acetylation of 5-chloro isome r to purify DOWELANCO (US) 1992-06-02 US claimed