SCHEMBL620233

SCHEMBL620233

NC(=O)c1cc(Cl)ccc1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.59
ALDH1A1 P00352 4/20 0.56
KDM4E B2RXH2 2/20 0.56
GLA P06280 1/20 0.56
GAA P10253 1/20 0.56
IKBKB O14920 1/20 0.53
FADS1 O60427 1/20 0.53
NOS2 P35228 2/20 0.53
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALOX15 P16050 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
GFER P55789 1/20 0.47
KMT2A Q03164 1/20 0.47
ABL1 P00519 1/20 0.47
TP53 P04637 1/20 0.47
GCK P35557 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8012538 0.98 RECQL (0.58) RECQLALDH1A1KDM4EGLAGAA
SCHEMBL9540049 0.84 RECQL (0.79) RECQLALDH1A1KDM4EFADS1NOS2
SCHEMBL5300577 0.84 IKBKB (0.71) RECQLKDM4EIKBKBGFERKMT2A
SCHEMBL31542015 0.83 ALDH1A1 (0.63) RECQLALDH1A1KDM4EGLAGAA
SCHEMBL15503392 0.83 RECQL (0.59) RECQLALDH1A1KDM4EFADS1NOS2
SCHEMBL220073 0.83 ALDH1A1 (0.63) RECQLALDH1A1KDM4EGLAGAA
SCHEMBL160570 0.83 ABL1 (0.61) RECQLALDH1A1KDM4EGLAGAA
SCHEMBL15134168 0.83 RECQL (0.59) RECQLALDH1A1KDM4EFADS1NOS2
SCHEMBL3790275 0.82 ALDH1A1 (0.60) RECQLALDH1A1KDM4EGLAGAA
SCHEMBL17565223 0.82 IKBKB (0.44) RECQLALDH1A1KDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010957-A Preparation method of fullerene pyrrolidine quinazolinone 湖北大学 2026-05-12 CN claimed
CN-120079371-A Oxygen vacancy-containing tungsten trioxide catalyst and preparation method and application thereof 南京理工大学 2025-06-03 CN claimed
CN-120040357-A Fluorescent probe of dicyanoisophorone derivative and application of fluorescent probe in Hg2+Application in detection 中国烟草总公司安徽省公司 2025-05-27 CN claimed
CN-120040356-A Small molecular fluorescent probe and application thereof in nickel ion detection 中国烟草总公司安徽省公司 2025-05-27 CN claimed
CN-117820337-A Preparation method of 12H-benzo [4,5] thiazolo [2,3-b ] quinazoline 12-ketone compound 赣南师范大学 2024-04-05 CN claimed
CN-113773265-B Fluorescent probe for detecting CYP450 and preparation method and application thereof 滨州医学院 2023-06-09 CN claimed
CN-112778288-B Near-infrared solid-state light-emitting fluorescent probe and preparation method and application thereof 湖南大学 2022-08-09 CN claimed
CN-113773265-A Fluorescent probe for detecting CYP450, preparation method and application thereof 滨州医学院 2021-12-10 CN claimed
CN-112778288-A Near-infrared solid-state light-emitting fluorescent probe and preparation method and application thereof 湖南大学 2021-05-11 CN claimed
CN-107367495-B A kind of sedimentation type alkaline phosphatase fluorescence probe and its synthetic method and application 湖南大学 2019-09-06 CN claimed
CN-104447580-A Method for synthesizing quinazolone compounds UNIV HUNAN 2015-03-25 CN claimed
CN-104447581-A Method for synthesizing N-heterocyclic compound UNIV HUNAN 2015-03-25 CN claimed
CN-103613550-A Environment-friendly synthesis method for 4(3H)-quinazolinone UNIV CHENGDU TECHNOLOGY 2014-03-05 CN claimed
CN-103570632-A Synthesis method of catalyst-free 4(3H)-quinazolinone UNIV CHENGDU TECHNOLOGY 2014-02-12 CN claimed
CN-102911126-A Synthesis of 2-aryl quinazolone from benzyl halide and 2-amobenzamide UNIV CHENGDU TECHNOLOGY 2013-02-06 CN claimed
CN-101575301-B Preparation method of 2-amino-5-chlorobenzamide UNIV NANKAI 2012-03-28 CN claimed
CN-101575301-A Preparation method of 2-amino-5-chlorobenzamide UNIV NANKAI (CN) 2009-11-11 CN claimed
EP-0236646-B1 ORTHO-ANISAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATIONS Laboratoires DELAGRANGE, Société Anonyme (FR) 1990-10-10 EP claimed
EP-0236646-A1 Ortho-anisamides, process for their preparation and their pharmaceutical applications Laboratoires DELAGRANGE, Société Anonyme (FR) 1987-09-16 EP claimed
CN-86105682-A Novel benzamides, process for their preparation and their use in therapy 1987-02-04 CN claimed