SCHEMBL2200817

SCHEMBL2200817

C=CN1C(=O)c2ccc(C(C)(C)C)cc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 6/20 0.49
CA1 P00915 4/20 0.49
CA12 O43570 3/20 0.49
CA2 P00918 4/20 0.48
NPC1 O15118 1/20 0.47
ALDH1A1 P00352 1/20 0.47
PLA2G1B P04054 1/20 0.47
NFKB1 P19838 1/20 0.47
CASP3 P42574 1/20 0.47
RAB9A P51151 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
NR1H3 Q13133 2/20 0.46
CA4 P22748 1/20 0.43
TNF P01375 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18434539 0.89 ALDH1A1 (0.44) CA9CA1CA12CA2NPC1
SCHEMBL2261723 0.83 PARP1 (0.37) CA9CA1CA12ALDH1A1NR1H3
SCHEMBL19702942 0.80 CA9 (0.53) CA9CA1CA12CA2NPC1
SCHEMBL15043754 0.79 CASP3 (0.51) CA9CA1CA12CA2NPC1
SCHEMBL15043753 0.78 NR1H3 (0.58) CA9CA1CA12CA2NPC1
SCHEMBL22022263 0.77 CA9 (0.53) CA9CA1CA12CA2NPC1
SCHEMBL14072404 0.74 NPC1 (0.53) CA9CA1CA12CA2NPC1
SCHEMBL12235644 0.74 CA9 (0.56) CA9CA1CA12CA2NPC1
SCHEMBL2156201 0.72 CA9 (0.56) CA9CA1CA12CA2NPC1
SCHEMBL15043752 0.71 CA9 (0.58) CA9CA1CA12CA2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2706402-B1 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS (US) 2017-02-01 EP claimed
US-9011992-B2 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS (US) 2015-04-21 US claimed
EP-2340461-B1 OPTICAL COMPENSATION FILMS BASED ON STRETCHED POLYMER FILMS AKRON POLYMER SYSTEMS (US) 2014-05-07 EP claimed
EP-2706402-A2 Optical compensation films based on stretched polymer films Akron Polymer Systems (US) 2014-03-12 EP claimed
US-8377558-B2 Optical compensation films with disk groups for liquid crystal display AKRON POLYMER SYSTEMS (US) 2013-02-19 US claimed
US-8226860-B2 Optical compensation films having positive birefringence for liquid crystal display AKRON POLYMER SYSTEMS (US) 2012-07-24 US claimed
US-20110251365-A1 Optical compensation films with disk groups for liquid crystal display HARRIS FRANK W 2011-10-13 US claimed
US-20090068380-A1 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS 2009-03-12 US claimed
US-20080241428-A1 Optical compensation films with disk groups for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US claimed
US-20080239491-A1 Optical compensation films having positive birefringence for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US claimed
EP-2135133-B1 OPTICAL COMPENSATION FILMS HAVING POSITIVE BIREFRINGENCE FOR LIQUID CRYSTAL DISPLAY AKRON POLYMER SYSTEMS (US) 2018-10-10 EP disclosed
US-9785011-B2 Liquid crystal display having improved wavelength dispersion characteristics AKRON POLYMER SYSTEMS (US) 2017-10-10 US disclosed
US-9785011-B2 Liquid crystal display having improved wavelength dispersion characteristics AKRON POLYMER SYSTEMS (US) 2017-10-10 US disclosed
US-9785011-B2 Liquid crystal display having improved wavelength dispersion characteristics AKRON POLYMER SYSTEMS (US) 2017-10-10 US disclosed
EP-2706402-B1 Optical compensation films based on stretched polymer films AKRON POLYMER SYSTEMS (US) 2017-02-01 EP disclosed
US-20080241427-A1 Optical retardation compensation film having positive C-plate and at least one negative C-plate; LCD device; optical switches and waveguides AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080241427-A1 Optical retardation compensation film having positive C-plate and at least one negative C-plate; LCD device; optical switches and waveguides AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080241427-A1 Optical retardation compensation film having positive C-plate and at least one negative C-plate; LCD device; optical switches and waveguides AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080239491-A1 Optical compensation films having positive birefringence for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed
US-20080239491-A1 Optical compensation films having positive birefringence for liquid crystal display AKRON POLYMER SYSTEMS 2008-10-02 US disclosed