Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 6/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200901 | 0.98 | GRIK1 (0.49) | GRIK1GRIK2CYP2C19NAAAHTT | |
| SCHEMBL25197311 | 0.98 | GRIK1 (0.49) | GRIK1GRIK2CYP2C19NAAAHTT | |
| SCHEMBL3450598 | 0.92 | GRIK1 (0.42) | GRIK1GRIK2CYP2C19GRIA1GRIA2 | |
| SCHEMBL23883371 | 0.86 | GRIK1 (0.42) | GRIK1GRIK2CYP2C19NAAAHTT | |
| Hydrochloric Acid SCHEMBL30921689 | 0.85 | CYP2C19 (0.46) | GRIK1GRIK2CYP2C19NAAAHTT | |
| SCHEMBL6535845 | 0.85 | CYP2C19 (0.50) | GRIK1GRIK2CYP2C19NAAAHTT | |
| SCHEMBL9503510 | 0.82 | NAAA (0.47) | GRIK1GRIK2CYP2C19NAAAHTT | |
| Hydrochloric Acid SCHEMBL30939844 | 0.81 | CYP2C19 (0.42) | CYP2C19NAAAHTTCYP19A1L3MBTL1 | |
| SCHEMBL1845737 | 0.81 | NAAA (0.49) | GRIK1GRIK2CYP2C19NAAAHTT | |
| SCHEMBL18071166 | 0.81 | NAAA (0.49) | GRIK1GRIK2CYP2C19NAAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138416-B1 | GROWTH HORMONE RELEASE FACTOR ANALOGS | ELI LILLY AND COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| US-4617149-A | ANIMAL GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1986-10-14 | — | — | US | disclosed |