Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ODC1 | P11926 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009123 | 1.00 | ARG1 (0.39) | ARG1ARG2CYP1A2ODC1CYP2D6 | |
| SCHEMBL16222693 | 0.84 | ARG1 (0.48) | ARG1ARG2CYP1A2ODC1CYP2D6 | |
| SCHEMBL16222763 | 0.84 | ARG1 (0.48) | ARG1ARG2CYP1A2ODC1CYP2D6 | |
| SCHEMBL22009572 | 0.79 | ARG1 (0.40) | ARG1ARG2CYP1A2ODC1CYP2D6 | |
| SCHEMBL22009377 | 0.79 | ARG1 (0.40) | ARG1ARG2CYP1A2ODC1CYP2D6 | |
| SCHEMBL28577951 | 0.79 | ARG1 (0.40) | ARG1ARG2CYP1A2ODC1CYP2D6 | |
| SCHEMBL16222670 | 0.78 | ARG1 (0.37) | ARG1ARG2CYP1A2ODC1KDM4E | |
| SCHEMBL11083886 | 0.78 | CYP1A2 (0.48) | ARG1ARG2CYP1A2ODC1CYP2D6 | |
| SCHEMBL16222764 | 0.78 | ARG1 (0.37) | ARG1ARG2CYP1A2ODC1KDM4E | |
| SCHEMBL4318235 | 0.77 | ARG1 (0.43) | ARG1ARG2ODC1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954537-B2 | Amino acids bearing a norbornene moiety | VALANX BIOTECH GMBH (AT) | 2021-03-23 | — | — | US | disclosed |
| US-20200157586-A1 | NOVEL AMINO ACIDS BEARING A NORBORNENE MOIETY | TECHNISCHE UNIVERSITÄT GRAZ (AT) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157586-A1 | NOVEL AMINO ACIDS BEARING A NORBORNENE MOIETY | BCAT1, BCAT2, NGLY1 | ARG1 780/4885ARG2 1254/4885CYP1A2 3233/4885 |
| US-10954537-B2 | Amino acids bearing a norbornene moiety | BCAT1, BCAT2, DNPEP | ARG1 875/4885ARG2 1477/4885CYP1A2 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.