Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ARG1 | P05089 | 4/20 | 0.50 |
| ▸ | ARG2 | P78540 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22009371 | 1.00 | ODC1 (0.56) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL10653529 | 0.86 | ARG1 (0.66) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL10653533 | 0.86 | ARG1 (0.66) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL28547233 | 0.86 | ODC1 (0.47) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL9501852 | 0.85 | ODC1 (0.56) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL8764682 | 0.83 | ODC1 (0.55) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL6757381 | 0.83 | ARG1 (0.49) | ODC1KDM4EARG1ARG2FDPS | |
| SCHEMBL11676322 | 0.83 | ARG1 (0.49) | ODC1KDM4EARG1ARG2FDPS | |
| SCHEMBL28218941 | 0.80 | ODC1 (0.66) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL21802412 | 0.78 | ODC1 (0.63) | ODC1LMNABLMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954537-B2 | Amino acids bearing a norbornene moiety | VALANX BIOTECH GMBH (AT) | 2021-03-23 | — | — | US | disclosed |
| US-20200157586-A1 | NOVEL AMINO ACIDS BEARING A NORBORNENE MOIETY | TECHNISCHE UNIVERSITÄT GRAZ (AT) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157586-A1 | NOVEL AMINO ACIDS BEARING A NORBORNENE MOIETY | BCAT1, BCAT2, NGLY1 | ODC1 651/4885LMNA 3612/4885BLM 4851/4885 |
| US-10954537-B2 | Amino acids bearing a norbornene moiety | BCAT1, BCAT2, DNPEP | ODC1 529/4885LMNA 3661/4885BLM 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.