Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27113739 | 0.94 | KIF11 (0.46) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1996992 | 0.82 | F2 (0.50) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL20625993 | 0.81 | CYP1A2 (0.40) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL27113737 | 0.81 | CNR1 (0.44) | KIF11 | |
| SCHEMBL6858733 | 0.79 | KIF11 (0.59) | KIF11KMT2AMEN1HTTNPC1 | |
| SCHEMBL15371169 | 0.79 | PRSS1 (0.52) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL23987229 | 0.77 | MAPT (0.42) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14107831 | 0.77 | KIF11 (0.41) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4603900 | 0.76 | IDO1 (0.39) | L3MBTL1KMT2AMEN1HTTNPC1 | |
| SCHEMBL22010458 | 0.76 | EPHX2 (0.39) | L3MBTL1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | NGLY1, GLMN, GMPS | L3MBTL1 473/4885F2 4017/4885PRSS1 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.