SCHEMBL1996992

SCHEMBL1996992

N=C(N)Nc1ccc(NC(=N)N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
TMPRSS6 Q8IU80 1/20 0.50
ST14 Q9Y5Y6 1/20 0.50
PEPD P12955 1/20 0.44
ALDH1A1 P00352 3/20 0.42
NPC1 O15118 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAPT P10636 2/20 0.40
RAB9A P51151 1/20 0.40
TP53 P04637 1/20 0.40
TYR P14679 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL399197 0.92 KIF11 (0.48) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL447770 0.89 PEPD (0.60) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL6880468 0.89 F2 (0.43) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL1438380 0.89 MAPT (0.56) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL166139 0.87 KIF11 (0.55) NPC1CYP3A4CYP2C19MAPTRAB9A
SCHEMBL10815124 0.87 PRSS1 (0.69) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL4029597 0.87 ALDH1A1 (0.61) F2PRSS1PRSS2PRSS3ST14
SCHEMBL1184889 0.87 SIGMAR1 (0.53) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL348736 0.87 F2 (0.42) F2PRSS1PRSS2PRSS3TMPRSS6
Hydrochloric Acid SCHEMBL10495490 0.87 MAPT (0.54) F2PRSS1PRSS2PRSS3TMPRSS6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020218835-A1 NOVEL POLYIMIDE-TYPE POLYMER AND PREPARATION METHOD THEREFOR 서울대학교 산학협력단 2020-10-29 WO claimed
CN-118749016-A Thermoplastic resin composition for hot melt lamination molding, molded body, and method for producing the same 株式会社ADEKA 2024-10-08 CN disclosed
CN-117143396-A Particulate ultraviolet absorber and resin composition 株式会社艾迪科 2023-12-01 CN disclosed
CN-117143033-A Particulate ultraviolet absorber and resin composition 株式会社艾迪科 2023-12-01 CN disclosed
CN-117143395-A Particulate ultraviolet absorber and resin composition 株式会社艾迪科 2023-12-01 CN disclosed
US-11779583-B2 Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction EMORY UNIVERSITY (US) 2023-10-10 US disclosed
CN-116813979-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-09-29 CN disclosed
CN-112004905-B Particulate ultraviolet absorber and resin composition 株式会社艾迪科 2023-08-22 CN disclosed
CN-112105704-B Particulate ultraviolet absorber and resin composition 株式会社艾迪科 2023-08-22 CN disclosed
CN-111936594-B Particulate ultraviolet absorber and resin composition 株式会社艾迪科 2023-08-18 CN disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016363-A1 CORROSION-INHIBITING COATING VENTURE LENDING & LEASING, IV, INC. 2004-01-29 US disclosed
WO-2004009869-A2 CORROSION-INHIBITING COATING FOR METAL SURFACES UNIVERSITY OF DAYTON (US) 2004-01-29 WO disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11779583-B2 Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction SHBG, ABAT, GLS F2 867/4885PRSS1 1088/4885PRSS2 1113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.