Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449227 | 1.00 | SELP (0.54) | SELPPPARGPPARACYP1A2PLAAT3 | |
| SCHEMBL1207379 | 0.92 | FFAR1 (0.57) | PPARGPPARAHPGDCDK8CLK4 | |
| Hydrochloric Acid SCHEMBL1375864 | 0.91 | FFAR1 (0.56) | PPARGPPARAHPGDCDK8CLK4 | |
| SCHEMBL503571 | 0.87 | PLAAT3 (0.61) | SELPPPARGPPARACYP1A2PLAAT3 | |
| SCHEMBL22010007 | 0.86 | MEN1 (0.46) | SELPPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8984890 | 0.86 | SELP (0.55) | SELPPPARGPPARACYP1A2PLAAT3 | |
| SCHEMBL1453516 | 0.84 | HPGD (0.66) | SELPPPARGPPARACYP1A2PLAAT3 | |
| SCHEMBL3686168 | 0.83 | SELP (0.53) | SELPPPARGPPARACYP1A2PLAAT3 | |
| SCHEMBL344964 | 0.83 | PPARG (0.54) | SELPPPARGPPARACYP1A2PLAAT3 | |
| SCHEMBL7095615 | 0.83 | PPARA (0.59) | SELPPPARGPPARAPLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249691-A | Bicyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20210077431-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | BEIJING GREATWAY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2021-03-18 | — | — | US | disclosed |
| EP-3653602-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | Beijing Greatway Pharmaceutical Technology Co., Ltd. (CN) | 2020-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077431-A1 | N-(2-(SUBSTITUTED-NAPHTH-1-YL)ETHYL) SUBSTITUTED AMIDE COMPOUND, PREPARATION AND USES THEREOF | MTNR1A, HTR2C, MTNR1B | SELP 1696/4885PPARG 395/4885PPARA 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.