Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209595 | 0.88 | ADRA2A (0.50) | ADRA2AADRA1AFNTAFNTBMAPT | |
| SCHEMBL3517702 | 0.80 | — | — | |
| SCHEMBL11357571 | 0.79 | ACE (0.46) | ADRA2AADRA1AFNTAFNTBMAPT | |
| SCHEMBL15617978 | 0.79 | ADRA2A (0.43) | ADRA2AADRA1AMAPTBLMTSHR | |
| SCHEMBL206960 | 0.78 | DGKA (0.54) | ADRA2AADRA1AFNTAFNTBMAPT | |
| SCHEMBL30309890 | 0.78 | ADRA2A (0.46) | ADRA2AADRA1AFNTAFNTBMAPT | |
| SCHEMBL7777490 | 0.78 | DGKA (0.48) | ADRA2AADRA1AFNTAFNTBMAPT | |
| SCHEMBL28466792 | 0.78 | FNTA (0.44) | ADRA2AADRA1AFNTAFNTBMAPT | |
| SCHEMBL7622921 | 0.77 | TSHR (0.59) | ADRA2AADRA1AFNTAFNTBMAPT | |
| SCHEMBL25781315 | 0.77 | ADRA2A (0.41) | ADRA2AADRA1AMAPTBLMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098658-A1 | 20-SUBSTITUTED CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 中国海洋大学 | 2020-05-22 | — | — | WO | disclosed |