Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033316 | 1.00 | LMNA (0.37) | LMNATP53NOTUMTHRBMAPT | |
| SCHEMBL30161678 | 1.00 | LMNA (0.37) | LMNATP53NOTUMTHRBMAPT | |
| SCHEMBL21963797 | 0.90 | LMNA (0.41) | LMNATP53NOTUMTHRBMAPT | |
| SCHEMBL31033306 | 0.84 | GPR119 (0.37) | LMNATP53NOTUMMAPTGHSR | |
| SCHEMBL22010480 | 0.84 | GPR119 (0.37) | LMNATP53NOTUMMAPTGHSR | |
| SCHEMBL30161412 | 0.84 | GPR119 (0.37) | LMNATP53NOTUMMAPTGHSR | |
| SCHEMBL21963860 | 0.78 | KMT2A (0.44) | KMT2A | |
| SCHEMBL31033286 | 0.77 | ALDH1A1 (0.40) | LMNAKMT2A | |
| SCHEMBL30161442 | 0.76 | — | — | |
| SCHEMBL21963920 | 0.74 | KCNH2 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272302-A | Antibiotic compounds, process for their manufacture, pharmaceutical compositions containing them and their use | 德彪药业国际股份公司 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |