Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25707381 | 0.82 | LMNA (0.39) | ESR1ESR2GAAMAPTKMT2A | |
| SCHEMBL21963701 | 0.81 | TOP2A (0.36) | ESR1ESR2GAAMAPTKMT2A | |
| SCHEMBL29958536 | 0.80 | GAA (0.34) | GAA | |
| SCHEMBL21963700 | 0.79 | KMT2A (0.39) | ESR1ESR2GAAKMT2A | |
| SCHEMBL24923371 | 0.79 | ESR1 (0.32) | ESR1ESR2GAA | |
| SCHEMBL28604517 | 0.78 | ESR2 (0.39) | ESR1ESR2GAA | |
| SCHEMBL21963757 | 0.74 | EGFR (0.33) | GAAKMT2A | |
| SCHEMBL22010749 | 0.74 | CA2 (0.39) | GAACA2NR1I3MAPTKMT2A | |
| SCHEMBL22010512 | 0.73 | GBA1 (0.34) | GAAKMT2A | |
| SCHEMBL21963733 | 0.73 | KMT2A (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |