SCHEMBL22010749

SCHEMBL22010749

CNCc1c(C)oc2c(O)cccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
MAOA P21397 9/20 0.38
EGFR P00533 1/20 0.38
ATP1A1 P05023 2/20 0.37
ATP1B1 P05026 2/20 0.37
ATP1A3 P13637 2/20 0.37
ATP1B2 P14415 2/20 0.37
ATP1A2 P50993 2/20 0.37
ATP1B3 P54709 2/20 0.37
FXYD2 P54710 2/20 0.37
ATP1A4 Q13733 2/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
NUDT1 P36639 1/20 0.36
RELA Q04206 1/20 0.36
MAOB P27338 2/20 0.35
GAA P10253 2/20 0.34
NR1I3 Q14994 1/20 0.34
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011035 0.81 LOXL2 (0.37) CA2MAOALOXL2MAOBNR1I3
SCHEMBL21963707 0.81 CA2 (0.39) CA2NR1I3CYP3A4
SCHEMBL21964002 0.76 GAA (0.39) CA2MAOAEGFRATP1A1ATP1B1
SCHEMBL22010747 0.74 ESR1 (0.38) CA2GAANR1I3MAPTKMT2A
SCHEMBL6454090 0.73 MAOA (0.46) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL24923419 0.73 MAOA (0.35) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL21964000 0.72 MAOA (0.37) MAOAEGFRATP1A1ATP1B1ATP1A3
Hydrochloric Acid SCHEMBL21964032 0.71 CA2 (0.60) CA2MAOANR1I3MEN1CYP1A2
SCHEMBL28610377 0.70 MAOA (0.43) MAOAEGFRATP1A1ATP1B1ATP1A3
SCHEMBL21963791 0.70 MTNR1B (0.40) MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099341-A1 ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF DEBIOPHARM INTERNATIONAL S.A. (CH) 2020-05-22 WO disclosed