SCHEMBL22011194

SCHEMBL22011194

CCCCCc1cnc(-c2cc3oc4cc(OCC)c(F)cc4c3c(F)c2F)nc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RARB P10826 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
PGAM1 P18669 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22010970 0.80 PGAM1 (0.42) L3MBTL1PGAM1
SCHEMBL22010821 0.77 RARB (0.36) MAPTRAB9ARARB
SCHEMBL29118536 0.76 PGAM1 (0.42) L3MBTL1PGAM1
SCHEMBL22010979 0.74
SCHEMBL22011189 0.73 RARB (0.37) MAPTRAB9AL3MBTL1RARBGPR55
SCHEMBL9548148 0.73 RARB (0.45) MAPTRAB9AL3MBTL1RARB
SCHEMBL9406337 0.73 RARB (0.45) MAPTRAB9AL3MBTL1RARB
SCHEMBL22010955 0.73 RARB (0.40) MAPTRAB9AL3MBTL1RARBGPR55
SCHEMBL22010835 0.72 RARB (0.40) MAPTRAB9AL3MBTL1RARBGPR55
SCHEMBL22010998 0.71 RARB (0.44) MAPTRAB9AL3MBTL1RARBGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 MAPT 1234/4885RAB9A 2387/4885L3MBTL1 427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.