SCHEMBL22010835

SCHEMBL22010835

CCCCCc1ccc(-c2ccc(-c3cc4oc5cc(OCC)c(F)c(F)c5c4c(F)c3F)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.40
RARA P10276 2/20 0.39
RARG P13631 1/20 0.39
ABCB1 P08183 1/20 0.38
MAPT P10636 4/20 0.38
RAB9A P51151 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MTOR P42345 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.34
GAA P10253 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22010955 0.99 RARB (0.40) RARBRARARARGABCB1MAPT
SCHEMBL22010998 0.91 RARB (0.44) RARBRARARARGABCB1MAPT
SCHEMBL22010820 0.91 RARB (0.40) RARBABCB1MPL
SCHEMBL22010988 0.89 MPL (0.37) RARBRARARARGABCB1MAPT
SCHEMBL22011803 0.85 CALM1 (0.35) MAPTRAB9AL3MBTL1FFAR4GPR55
SCHEMBL22011189 0.85 RARB (0.37) RARBRARARARGMAPTRAB9A
SCHEMBL22011104 0.84 NAAA (0.33) RARBRARARARGMAPTRAB9A
SCHEMBL22011081 0.83 MAOB (0.36) ABCB1ALDH1A1MEN1KMT2AHPGD
SCHEMBL22011813 0.83 S1PR1 (0.35) MAPTRAB9AL3MBTL1
SCHEMBL22011103 0.82 RARB (0.42) RARBRARARARGABCB1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662378-B2 Compound having fluorodibenzofuran ring, liquid crystal composition and liquid crystal display device YBX1, ZKSCAN2, RCC1 RARB 2226/4885RARA 1881/4885RARG 3543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.