SCHEMBL22011544

SCHEMBL22011544

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4c6oc7ccccc7c6c6c(ccc7oc8ccccc8c76)c4n5-c4ccccc4)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 3/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPARG P37231 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
NR2E3 Q9Y5X4 1/20 0.32
NCOR2 Q9Y618 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
LMNA P02545 1/20 0.31
PLA2G10 O15496 1/20 0.31
TSPO P30536 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22011545 0.97 KDM4E (0.38) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL24172257 0.95 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL22011970 0.93 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL22011543 0.91 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL22011538 0.90 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL22011968 0.88 KDM4E (0.38) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL16641287 0.88 KDM4E (0.45) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL22011531 0.88 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL16996598 0.85 KDM4E (0.47) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL22011534 0.85 WNK1 (0.34) KDM4EATML3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-01-06 US disclosed
WO-2020099307-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220006030-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES ZYX, RER1, AOC2 KDM4E 1792/4885ATM 1787/4885L3MBTL1 2301/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 KDM4E 1792/4885ATM 1787/4885L3MBTL1 2301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.