Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669274 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL17448527 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL669273 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL287478 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL15661104 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL19514107 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL63468 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL6032229 | 0.76 | — | — | |
| SCHEMBL5713308 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL31325622 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRKIF11CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | claimed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | claimed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | claimed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | claimed |
| CN-112279940-B | Acylphosphine photoinitiator and preparation method thereof | 山东科技大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-114957053-A | Oxoethylene compound or pharmaceutically acceptable salt thereof, preparation method and application thereof, pharmaceutical composition and application thereof | 中国医学科学院医药生物技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| CN-110483576-B | Phosphine-containing fused heterocyclic compound and preparation method and application thereof | 宁波卢米蓝新材料有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-112279940-A | Acylphosphine photoinitiator and preparation method thereof | 山东科技大学 | 2021-01-29 | — | — | CN | disclosed |
| US-20160016860-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DUBLIN CITY UNIVERSITY (IE) | 2016-01-21 | — | — | US | disclosed |
| EP-2970347-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | Dublin City University (IE) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014140353-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DUBLIN CITY UNIVERSITY (IE) | 2014-09-18 | — | — | WO | disclosed |
| US-7977499-B2 | Bis(ferrocenylphosphino) ferrocene ligands used in asymmetric hydrogenation reactions | SOLVIAS AG (CH) | 2011-07-12 | — | — | US | disclosed |
| US-20100160660-A1 | BIS(FERROCENYLPHOSPHINO) FERROCENE LIGANDS USED IN ASSYMETRIC HYDROGENATION REACTIONS | SOLVIAS AG (CH) | 2010-06-24 | — | — | US | disclosed |
| EP-2125210-A1 | BIS (FERROCENYLPHOSPHINO) FERROCENE LIGANDS USED IN ASYMMETRIC HYDROGENATION REACTIONS | Solvias AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| EP-1354886-B1 | Process for the preparation of tertiary phosphines | SALTIGO GMBH (DE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008101868-A1 | BIS (FERROCENYLPHOSPHINO) FERROCENE LIGANDS USED IN ASYMMETRIC HYDROGENATION REACTIONS | SOLVIAS AG (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20070299273-A1 | prepared by reacting phosphorus halide with organomagnesium compound in presence of copper compound; di(tert-butyl)phenylphosphonium tetrafluoroborate, for example | LANXESS DEUTSCHLAND GMBH (DE) | 2007-12-27 | — | — | US | disclosed |
| US-7230136-B2 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20030229240-A1 | Reacting phosphorus halide with organomagnesium compound in presence of copper compound | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016860-A1 | METHODS FOR PHOSPHINE OXIDE REDUCTION IN CATALYTIC WITTIG REACTIONS | DCXR, TECR, PWWP2B | ALDH1A1 4341/4885TSHR 707/4885KIF11 4432/4885 |
| US-20100160660-A1 | BIS(FERROCENYLPHOSPHINO) FERROCENE LIGANDS USED IN ASSYMETRIC HYDROGENATION REACTIONS | FTH1, HRH4, HRH3 | ALDH1A1 818/4885TSHR 724/4885KIF11 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.