Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585157 | 0.80 | CYP11B1 (0.35) | — | |
| SCHEMBL20681369 | 0.71 | NLRP3 (0.38) | NLRP3UGT2B17 | |
| SCHEMBL22012824 | 0.71 | NLRP3 (0.40) | NLRP3UGT2B17 | |
| SCHEMBL22002675 | 0.71 | NLRP3 (0.40) | NLRP3UGT2B17 | |
| SCHEMBL22282197 | 0.71 | NLRP3 (0.38) | NLRP3UGT2B17 | |
| SCHEMBL30770437 | 0.71 | NLRP3 (0.38) | NLRP3UGT2B17 | |
| SCHEMBL20692313 | 0.71 | NLRP3 (0.40) | NLRP3UGT2B17 | |
| SCHEMBL12056687 | 0.71 | MTNR1A (0.51) | — | |
| SCHEMBL23944932 | 0.69 | PARP1 (0.46) | PARP1BCL2L1BADCES1 | |
| SCHEMBL12506888 | 0.69 | UGT2B17 (0.40) | BRD3UGT2B17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |