Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360559 | 0.85 | NPC1 (0.34) | — | |
| SCHEMBL11477879 | 0.76 | SLC6A2 (0.33) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL18360431 | 0.75 | NPC1 (0.36) | — | |
| SCHEMBL16942857 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL20137505 | 0.74 | SMN1; SMN2 (0.34) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL17888678 | 0.74 | DUT (0.33) | — | |
| SCHEMBL3793194 | 0.73 | SLC6A2 (0.33) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL24156261 | 0.72 | HRH1 (0.32) | — | |
| SCHEMBL87084 | 0.72 | SLC6A4 (0.36) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL11470901 | 0.72 | NPC1 (0.45) | SLC6A2HTR2AHTR2CSLC6A4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662193-B2 | Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins | AC IMMUNE SA (CH) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662193-B2 | Carbazole and carboline compounds for use in the diagnosis, treatment, alleviation or prevention of disorders associated with amyloid or amyloid-like proteins | APP, BACE1, PSEN1 | SLC6A2 529/4885HTR2A 945/4885HTR2C 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.