SCHEMBL87084

SCHEMBL87084

COCCOC1CCNCC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 13/20 0.36
SLC6A2 P23975 12/20 0.35
SLC6A3 Q01959 9/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35
HTR3A P46098 1/20 0.35
HTR4 Q13639 1/20 0.35
HRH1 P35367 2/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL77417 0.98 SLC6A4 (0.36) SLC6A4SLC6A2SLC6A3HTR2AHTR2C
SCHEMBL17309305 0.94 SLC6A4 (0.33) SLC6A4SLC6A2SLC6A3HTR2AHTR2C
SCHEMBL27389747 0.94 SLC6A4 (0.33) SLC6A4SLC6A2SLC6A3HTR2AHTR2C
SCHEMBL15362827 0.94 SLC6A4 (0.33) SLC6A4SLC6A2SLC6A3HTR2AHTR2C
Hydrochloric Acid SCHEMBL17293798 0.92 SLC6A4 (0.33) SLC6A4SLC6A2SLC6A3HTR2AHTR2C
Hydrochloric Acid SCHEMBL15352369 0.92 SLC6A4 (0.33) SLC6A4SLC6A2SLC6A3HTR2AHTR2C
SCHEMBL6043580 0.87 SLC6A4 (0.35) SLC6A4SLC6A2SLC6A3HTR2AHTR2C
SCHEMBL18912341 0.87 CHRM1 (0.39) SLC6A4SLC6A2SLC6A3
SCHEMBL13853932 0.87 CHRM1 (0.39) SLC6A4SLC6A2SLC6A3
SCHEMBL21638302 0.87 CHRM1 (0.39) SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4029868-B1 MCL-1 INHIBITORS GILEAD SCIENCES INC (US) 2026-05-20 EP disclosed
US-20260109677-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS INC (US) 2026-04-23 US disclosed
US-12522571-B2 Compounds, devices, and uses thereof SIGILON THERAPEUTICS, INC. (US) 2026-01-13 US disclosed
US-20250257057-A1 BICYCLIC CX3CR1 RECEPTOR AGONISTS GOLGI NEUROSCIENCES S.R.I. (IT) 2025-08-14 US disclosed
US-12258337-B2 Bicyclic CX3CR1 receptor agonists BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-03-25 US disclosed
US-12144816-B2 Substituted indole Mcl-1 inhibitors VANDERBILT UNIVERSITY (US) 2024-11-19 US disclosed
US-20240279187-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. 2024-08-22 US disclosed
CN-114929681-B Bicyclic CX3CR1 receptor agonists 德州大学系统董事会 2024-05-14 CN disclosed
US-20240150332-A1 BICYCLIC CX3CR1 RECEPTOR AGONISTS GOLGI NEUROSCIENCES S.R.L. (IT) 2024-05-09 US disclosed
US-11958839-B2 Bicyclic CX3CR1 receptor agonists BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-04-16 US disclosed
EP-1945220-A1 PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS CANNABINOID RECEPTOR ANTAGONISTS Mitsubishi Tanabe Pharma Corporation (JP) 2008-07-23 EP disclosed
US-20070244090-A9 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSPHORYLASE BRADLEY STUART E 2007-10-18 US disclosed
US-20070244090-A9 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSPHORYLASE BRADLEY STUART E 2007-10-18 US disclosed
EP-1812445-A1 PHARMACEUTICAL COMPOUNDS Piramed Limited (GB) 2007-08-01 EP disclosed
WO-2007046548-A1 PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS CANNABINOID RECEPTOR ANTAGONISTS MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-04-26 WO disclosed
US-20070049593-A1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor JAPAN TOBACCO INC. (JP) 2007-03-01 US disclosed
US-20070049593-A1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor JAPAN TOBACCO INC. (JP) 2007-03-01 US disclosed
CN-1826340-A Pyrrolopyridine-2-carboxylic acid amides as glycogen phosphorylase inhibitors PROSIDION LTD (GB) 2006-08-30 CN disclosed
WO-2006046031-A1 PHARMACEUTICAL COMPOUNDS PIRAMED LIMITED (GB) 2006-05-04 WO disclosed
US-4237138-A REGULATORS OF CARDIOVASCULAR SYSTEM PFIZER INC. (US) 1980-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049593-A1 Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor POLI, TERT, ZC3HAV1 SLC6A4 4166/4885SLC6A2 4036/4885SLC6A3 2991/4885
US-12258337-B2 Bicyclic CX3CR1 receptor agonists CX3CR1, CCR2, CCR5 SLC6A4 2786/4885SLC6A2 3547/4885SLC6A3 2555/4885
US-12144816-B2 Substituted indole Mcl-1 inhibitors MCL1, BCL2L1, BCL9 SLC6A4 3787/4885SLC6A2 3760/4885SLC6A3 3711/4885
US-20250257057-A1 BICYCLIC CX3CR1 RECEPTOR AGONISTS CX3CR1, CCR2, CCR5 SLC6A4 2786/4885SLC6A2 3547/4885SLC6A3 2555/4885
US-20070244090-A9 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSPHORYLASE PYGL, PYGM, PYGB SLC6A4 4170/4885SLC6A2 3258/4885SLC6A3 4298/4885
US-20240279187-A1 COMPOUNDS, DEVICES, AND USES THEREOF SLC10A1, SLCO1B3, SLC5A1 SLC6A4 204/4885SLC6A2 61/4885SLC6A3 130/4885
US-11958839-B2 Bicyclic CX3CR1 receptor agonists CX3CR1, CCR2, CCR5 SLC6A4 2786/4885SLC6A2 3547/4885SLC6A3 2555/4885
US-20260109677-A1 COMPOUNDS, DEVICES, AND USES THEREOF NR3C2, AGTR1, CHRM1 SLC6A4 1107/4885SLC6A2 311/4885SLC6A3 436/4885
US-20240150332-A1 BICYCLIC CX3CR1 RECEPTOR AGONISTS CX3CR1, CCR2, CCR5 SLC6A4 2786/4885SLC6A2 3547/4885SLC6A3 2555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.