Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | KCNB1 | Q14721 | 2/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567332 | 0.76 | POLB (0.32) | L3MBTL1 | |
| SCHEMBL20680949 | 0.76 | POLB (0.32) | L3MBTL1 | |
| SCHEMBL20698984 | 0.73 | THRA (0.31) | — | |
| SCHEMBL25138899 | 0.72 | L3MBTL1 (0.34) | L3MBTL1KCNA5KCNH2KCNB1KCNK2 | |
| SCHEMBL22002752 | 0.72 | GLA (0.41) | L3MBTL1 | |
| SCHEMBL30791047 | 0.70 | ATM (0.37) | KCNA5KCNH2KCNB1KCNK2 | |
| SCHEMBL20681103 | 0.70 | ATM (0.37) | KCNA5KCNH2KCNB1KCNK2 | |
| SCHEMBL25138967 | 0.69 | DRD1 (0.30) | — | |
| SCHEMBL20692160 | 0.68 | GABRA1 (0.38) | L3MBTL1 | |
| SCHEMBL20680908 | 0.66 | POLB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |