Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.34 |
| ▸ | GCKR | Q14397 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020730 | 0.88 | FFAR2 (0.36) | GCKGCKRSYKLOXL2 | |
| SCHEMBL22021271 | 0.87 | GCK (0.36) | GCKGCKRSYKLOXL2 | |
| SCHEMBL22013608 | 0.87 | GCK (0.36) | GCKGCKRSYKLOXL2 | |
| SCHEMBL30243995 | 0.87 | GCK (0.36) | GCKGCKRSYKLOXL2 | |
| SCHEMBL22020118 | 0.86 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL21962745 | 0.83 | GCK (0.37) | GCKGCKRSYKLOXL2 | |
| SCHEMBL21962597 | 0.83 | GCK (0.37) | GCKGCKRSYKLOXL2 | |
| SCHEMBL30276846 | 0.83 | GCK (0.37) | GCKGCKRSYKLOXL2 | |
| SCHEMBL21962161 | 0.83 | GCK (0.37) | GCKGCKRSYKLOXL2 | |
| SCHEMBL24499800 | 0.80 | LOXL2 (0.34) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |