Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.36 |
| ▸ | GCKR | Q14397 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22021271 | 1.00 | GCK (0.36) | GCKGCKRLOXL2SYK | |
| SCHEMBL22013608 | 1.00 | GCK (0.36) | GCKGCKRLOXL2SYK | |
| SCHEMBL21962745 | 0.88 | GCK (0.37) | GCKGCKRLOXL2SYK | |
| SCHEMBL21962161 | 0.88 | GCK (0.37) | GCKGCKRLOXL2SYK | |
| SCHEMBL30276846 | 0.88 | GCK (0.37) | GCKGCKRLOXL2SYK | |
| SCHEMBL21962597 | 0.88 | GCK (0.37) | GCKGCKRLOXL2SYK | |
| SCHEMBL22012513 | 0.87 | GCK (0.34) | GCKGCKRLOXL2SYK | |
| SCHEMBL22012765 | 0.87 | LOXL2 (0.33) | GCKGCKRLOXL2 | |
| SCHEMBL20680910 | 0.84 | LOXL2 (0.32) | GCKGCKRLOXL2 | |
| SCHEMBL22020730 | 0.83 | FFAR2 (0.36) | GCKGCKRLOXL2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230051589-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | GCK 1992/4885GCKR 365/4885LOXL2 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.